Research Papers

Curious about what makes DHYANCARE’s natural formulations different? Backed by clinical studies—explore the research below to discover the science behind our ingredients and their health benefits.

 

COLLAGEN PEPTIDE

JOINT HEALTH

1.      Efficacy and safety of low-molecular-weight collagen peptides in knee osteoarthritis: a randomized, double-blind, placebo-controlled trial. (Park et al., 2025)

2.      The effect of supplementation with type I and type III collagen peptide and type II hydrolyzed collagen on pain, quality of life and physical function in patients with meniscopathy: a randomized, double-blind, placebo-controlled study. (Genç et al., (2025).

3.      Evaluation of the Efficacy and Safety of CollaSel PRO® Type I and Type III Hydrolyzed Collagen Peptides in the Treatment of Osteoarthritis: A Double-Blind, Placebo-Controlled, Randomized Clinical Trial. Demir-Dora et al., 2025).

4.      Impact of Specific Bioactive Collagen Peptides on Joint Discomforts in the Lower Extremity during Daily Activities: A Randomized Controlled Trial. (Schulze et al., 2024)

5.      Oral supplementation with fish cartilage hydrolysate in an adult population suffering from knee pain and function discomfort: results from an innovative approach combining an exploratory clinical study and an ex-vivo clinical investigation. (Yves et al., 2023)

6.      The Influence of Specific Bioactive Collagen Peptides on Knee Joint Discomfort in Young Physically Active Adults: A Randomized Controlled Trial. (Zdzieblik et al., 2021)

7.      An Observational 1-Month Trial on the Efficacy and Safety of Promerim for Improving Knee Joint (Kilinc et al., 2018).

8.      Daily oral supplementation with collagen peptides combined with vitamins and other bioactive compounds improves skin elasticity and has a beneficial effect on joint and general wellbeing (Czajka et al., 2018).

9.      24-Week study on the use of collagen hydrolysate as a dietary supplement in athletes with activity-related joint pain (Clark et al., 2008).

 

SKIN HEALTH

1.      The Sustained Effects of Bioactive Collagen Peptides on Skin Health: A Randomized, Double-Blind, Placebo-Controlled Clinical Study. (Wang et al., 2025)

2.      Low-molecular-weight collagen peptides supplement promotes a healthy skin: A randomized, double-blinded, placebo-controlled study. (Seong et al., 2024)

3.      Oral intake of collagen peptide NS improves hydration, elasticity, desquamation, and wrinkling in human skin: a randomized, double blinded, placebo-controlled study (Lee et al., 2023).

4.      Effect of an Oral Nutrition Supplement Containing Collagen Peptides on Stratum Corneum Hydration and Skin Elasticity in Hospitalized Older Adults: A Multicenter Open-label Randomized Controlled Study. (Nomoto et al., 2020). 

5.      A randomized, triple-blind, placebo controlled, parallel study to evaluate the efficacy of a freshwater marine collagen on skin wrinkles and elasticity (Evans et al., 2021).

6.      Oral Supplementation with Hydrolyzed Fish Cartilage Improves the Morphological and Structural Characteristics of the Skin: A Double-Blind, Placebo-Controlled Clinical Study (Maia et al., 2021).

 

MORINGA SEED EXTRACT

JOINT HEALTH

1.      Alleviating the physical discomfort in healthy individuals with Moringa seed extract: a randomized, double-blind, placebo-controlled, parallel group trial (Aya et al., 2023).

2.      Impact of Moringa Seed Extract on Daily Fatigue and Low Back Pain: A Randomized, Parallel, Double-Blind, and Placebo-Controlled Study. (Kazuo et al., 2019).

 

TOXICITY & SAFETY

Assessment of Acute Toxicity, LD50 and Histopathological Evaluation of Nigella sativa and Moringa oleifera Seed Extracts in Wistar Rats. Tropical (Dibua et al., 2022).